Scientists at Rutgers University say they have identified a gene that may help understand obesity and its treatment. The research also helped discover the molecular function of the gene’s protein product. The researches said the human protein known as lipin is a key fat-regulating enzyme. “Lipin activity may be an important pharmaceutical target for the control of body fat in humans, treating conditions that range from obesity to the loss of fat beneath the skin, as seen in HIV patients,” said Prof. George M. Carman. The findings are published online by the Journal of Biological Chemistry. Previous studies with mice have shown that a lack of lipin causes a loss of body fat, whereas an excess of lipin promotes extra body fat. © Copyright 2006 by United Press International

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